The Mid-America Union Conference is preceded by the Central Union (1902-1980) and the Northern Union (1902-1932, 1937-1980) conferences. The Central Union Conference was formed April 17, 1902 in Topeka, Kansas, and encompassed Colorado, Iowa, Kansas, Missouri, and Nebraska. The Northern Union Conference was also formed in April 1902 and included Minnesota, North Dakota, South Dakota, and Wyoming, United States; and Alberta, Manitoba, and Saskatchewan, Canada (in 1907 the Canadian provinces were restructured into the Western Canadian Union Conference, and Iowa Conference was added to the Northern Union).

C W Flaiz
1902-1904
Northern Union

R A Underwood
1904-1912
Northern Union

Charles Thompson
1912-1919 & 1924-1932
Northern Union

C F McVagh
1919-1920
Northern Union

E T Russell
1920-1924
Northern Union

E H Oswald
1937-1941
Northern Union

M V Campbell
1941-1946
Northern Union

Jere D Smith
1946-1954
Northern Union

R H Nightingale
1954-1962
Northern Union

J L Dittberner
1962-1971
Northern Union

Arthur Kiesz
1971-1973
Northern Union

W O Coe
1973-1975
Northern Union

L J Leiske
1975-1977
Northern Union

E L Marley
1977-1980
Northern Union

E T Russell
1902-1914
Central Union

R A Underwood
1914-1920
Central Union

S E Wight
1920-1928
Central Union

M L Rice
1928
Central Union

J J Nethery
1928-1932
Central Union

J F Piper
1932-1942
Central Union

N C Wilson
1942-1946
Central Union

W H Branson
1946
Central Union

M V Campbell
1946-1954
Central Union

Jere D Smith
1954-1957
Central Union

Theodore Carcich
1957-1962
Central Union

R H Nightingale
1962-1975
Central Union

W O Coe
1975-1978
Central Union

E S Reile
1978-1980
Central Union

E S Reile
1980-1983
Mid-America Union

Joel O Tompkins
1983-1995
Mid-America Union

Charles Sandefur Jr
1995-2001
Mid-America Union

Dennis N Carlson
2001-2008
Mid-America Union

Roscoe J Howard III
2008-2011
Mid-America Union

Thomas Lemon
2011-2015
Mid-America Union

Gary Thurber
2015-
Mid-America Union